Fibroblast growth factors are signaling peptides that controls important cellular processes such as proliferation, differentiation, migration, adhesion and survival. Through binding to different types of receptors on the cell surface, these peptides can have different effect on the target cell. Which effect that is achieved depends on many factors. Thus, each of the 24 known FGFs different biological responses. The FGF receptors (FGFR 1-4) initiates different intracellular pathways which in turn leads to different biological responses.

As well as other politic fields, the cultural politics adapt to changes in society. The development in society has brought attention to the interaction between the cultural field and the economic field. One of the main goals within Swedish Cultural Policies today is the development of cultural and creative economics. Politicians and researchers claim that culture can be a significant part in economic growth in cities and making a place attractive to live in.I became interested in the discussion around the cultural experience as a factor of economic growth when I participated in a seminar at Karlstad CCC during Kulturparlamentet 2012. When I then started working at the music festival Putte i Parken during the spring of 2013 I thought about making this study.The main aim is to investigate in which way Putte i Parken can be a factor of growth and a factor of making Karlstad an attractive place to live in by analyzing documents, reports and literature in a qualitative way of working.

The Sub-Saharan countries have for a long time struggled with poverty and conflicts which might have proven hostile for investors. The analysis aims to see if there is a significant correlation between foreign direct investments (FDI) and economic growth and which cultural and institutional factors seem to be significant in this correlation. Considered are also other variables and their influence that might explain what motivates and gives incentives for foreign direct investments (FDI) and are used in the construction of a regression analysis. This to see whether there is an effect on the economic growth in relations to FDI. The results show that FDI is of significance to the economic growth in the region and the study shows that corruption seems to be the most significant institutional factor in the correlation with effect on economic growth and the ability to attract FDI..

The Sub-Saharan countries have for a long time struggled with poverty and conflicts which might have proven hostile for investors. The analysis aims to see if there is a significant correlation between foreign direct investments (FDI) and economic growth and which cultural and institutional factors seem to be significant in this correlation. Considered are also other variables and their influence that might explain what motivates and gives incentives for foreign direct investments (FDI) and are used in the construction of a regression analysis. This to see whether there is an effect on the economic growth in relations to FDI. The results show that FDI is of significance to the economic growth in the region and the study shows that corruption seems to be the most significant institutional factor in the correlation with effect on economic growth and the ability to attract FDI..

Trees of Bergvik apple (Bergviksäpple) planted between 2001 and 2007 have shown varying harvest. This study investigates why some trees gets low or no harvest while others get significantly higher harvest. The aim is to identify some reasons why fruiting differs between the trees and if possible suggest and/or enlighten the tree owners what can be done to improve fruiting. The study includes 25 trees, mostly located in Hälsingland, Sweden. The tree owners have answered two questionnaires, first in the spring with questions regarding flowering and the second in the autumn, regarding harvest.

Syndecan-1 is a cell surface proteoglycan which participates in cell adhesion, differentiation, motility, morphogenesis and intracellular signaling. The two glycosaminoglycans heparan sulfate and chondroitin sulfate are covalently attached to the ectodomain of syndecan-1 via a tetra saccharide linkage sequence. However, the ectodomain can be modified having only one or neither of the glycosaminglycans attached. The glycosaminoglycans are capable of binding ligands such as Fibroblast growth factors (FGFs) and support activation of receptors. The ectodomain is proteolytically cleaved from the cell surface by metalloproteinases in a process known as shedding.

Background: Today small business firms represent a considerable part of swedish economy, and the number of small firms has steadily increased the last ten years in relation to the total employment. The fact that there are firms willing to grow, it ought to be interesting observing their motives of growth, and what kind of strategies that can be identifiable in these firms. Purpose: To examine the motives of growth in small business firms, and to study which growth strategies the firms use when expanding their business. Realization: The study is accomplished through telephone interviews with six small business firms in the province of Jönköping. The firms contain between 10-49 employees.

Picropodophyllin (PPP) is an analogue of the anti tumour lignan podophyllotoxin with the unique ability to selectively inhibit the receptor of Insulin like growth factor 1(IGF-1). IGF-1 is believed to play an important part in development of the endometrium facing implantation. With PPP treated mice, studies can be made to measure gene expression from tissue of both treated and untreated mice to compare the role of IGF-1 regarding ovulation, implantation and receptivity. The aim of this study was to analyze gene expression of some steroid hormone receptors and cytokines in ovaries from mice treated with PPP. In this study, seven mice were treated with PPP at different times and tissue was collected.

The interest in businesses active on the countryside and their funding situation has increased in recent years. In a survey, conducted by Leif Berndtsson (2003), it was reported that there is a lack of external capital in rural areas. According to Berndtsson (2003) the lack of external capital inhibits the rural firm?s growth. The essay attempts to answer whether the shortage of external capital is a factor that inhibits development for rural businesses.

SammanfattningProjektgrupp 14-X5 avser med denna rapport att ge avdelningen Bioreagens på Thermo Fisher Scientific ett underlag för att på sikt kunna byta ut fetalt kalvserum (FCS) mot ett kemiskt definierat suplement vid odling av mushybridomceller för produktion av monoklonala antikroppar. Thermo Fisher Scientific är ett världsomspännande bioteknikföretag som utvecklar blodtestsystem som stöd för klinisk diagnos och uppföljning av allergier, astma och autoimmuna sjukdomar.Fetalt kalvserum är en tillsats i många odlingsmedier som ofta är nödvändig för att cellerna ska växa. Det finns dock många problem med FCS. Det är en biprodukt av köttindustrin och produceras på ett etiskt tveksamt sätt, variation mellan olika batcher förekommer och då det är en animalisk produkt finns en risk för kontamination av bland annat bakterier, virus och prioner. Av dessa anledningar vill man byta ut FCS mot ett kemiskt definierat, serumfritt supplement.

Syftet med denna litteraturöversikt är att göra en utvärdering över de mekanismer som är viktiga vid tumörmetastasers nybildning av kärl s.k. angiogenes och med vilka metoder man kan hindra dem. Tumörceller som prolifererar ohämmat utan att stimulera angiogenes begränsas av brist på näring och ineffektiv bortförsel av slaggprodukter och kan därför sällan växa och bli större än cirka 1mm. Detta medför att även om det kliniskt finns många små metastaser i en patient så innebär det sällan något problem för patienten. Om tumörcellerna däremot muterar så att de kan stimulera angiogenes så tillåts tumörerna växa sig större och förstör då kringliggande vävnad vilket tillslut resulterar i patientens död. Mycket forskning görs i nuläget inom ämnesområdet och man har som mål att med hjälp av angiogeneshämmare göra cancer till en kronisk men hanterbar sjukdom istället för den sjukdom med dödlig utgång som den ofta är idag. Den första angiogeneshämmaren som godkändes för medicinskt bruk i USA var Avastin (Bevacizumab) som är en antikropp som binder till och oskadliggör vascular endothelial growth factor (VEGF), vilket är en av de faktorer som stimulerar angiogenes. Detta får som följd att de tumörer (60 % av alla humana) som uttrycker denna faktor hämmas i sin tillväxt.

This bachelor thesis examines the relation between countries? degree of economic freedom and their economic performance. Economic freedom as a concept is defined as the degree of market economy within a nation.The variable of measure that is used is the Frasier institute Economic freedom of the world index (EFI). The paper is built upon the Solow growth model and is extended by incorporation of additional variables; among which of course economic freedom. The study is performed through regression analysis, based on the neoclassical model both on rich countries, poor countries and on all investigated countries.Two investigations are performed: i) the impact from economic freedom on countries level of GDP per capita and ii) the impact from economic freedom on the growth rate in GDP per capita.The finding is that economic freedom can be seen as a relevant determinant of differences in GDP per capita growth rates between nations.

Emissions of radionuclides to the atmosphere can lead to wet deposition on plants in the event of rainfall. An increased level of radioactivity in the plants may occur due to interception and retention of the radionuclides. If the content of the plants is above the threshold limit value, entire yields may have to be destroyed. In order to prevent contamination or decrease the content countermeasures can be taken. The impact of the biomass, leaf area index (LAI) and growth stage of the plant on the interception and retention is important to know in order to decide which countermeasures to use. Weather may also be an important factor. In this work the interception and retention of 134Cs and 85Sr by spring wheat, ley and spring oil-seed rape was studied.

Heifer?s growth may be divided into three main phases: calf period, puberty and pregnancy. When the heifers are about three months old a critical period begins. This period ends when the heifer reach puberty and have her first oestrus at around 9-12 months of age. In the critical period the mammary gland starts to grow at a fast rate and Insulin-like growth factor-1 (IGF-1) transport the growth signals to the mammary glands.

The economic growth we have experienced the last century is based on limited natural resources. Whether these resources will last for a further economic growth is widely debated. Pessimism and optimism have each been influential philosophies in debate whose opinions can be conceded as two opposing opinions. In this paper we have analyze these opinions from an economics perspective. To study this further, the construction and meaning of the pessimistic and optimistic arguments have been applied implicitly on the Leontief production function and the Solow growth model.